5-azidovaleric acid methyl ester
5-Azidopentanoic acid methyl ester
CAS: 127811-93-2
Molecular Formula: C6H11N3O2
5-azidovaleric acid methyl ester - Names and Identifiers
| Name | 5-Azidopentanoic acid methyl ester |
| Synonyms | methyl 5-azidopentanoate 5-azidovaleric acid methyl ester 5-Azidopentanoic acid methyl ester 5-Azidopentanoic acid Methyl ester |
| CAS | 127811-93-2 |
5-azidovaleric acid methyl ester - Physico-chemical Properties
| Molecular Formula | C6H11N3O2 |
| Molar Mass | 157.17044 |
5-azidovaleric acid methyl ester - Introduction
5-Azidopentanoic acid methyl ester (methyl 5-azidopentanoate) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow oily liquid.
-Molecular formula: C6H9N3O2.
-Molecular weight: 155.16g/mol.
-Melting Point: Unknown.
-Boiling point: 215-220°C(0.15 mmHg).
-Solubility: Soluble in most organic solvents, such as ethanol, chloroform and dimethylformamide.
Use:
- 5-Azidopentanoic acid methyl ester is a commonly used chemical reagent, which is widely used in organic synthesis and biochemical research.
-It can be used as a donor for azido groups, and an alkyne click reaction (click chemistry) occurs during the synthesis process, which is used to build a variety of biologically active molecules.
Preparation Method:
-The synthesis of 5-Azidopentanoic acid methyl ester is usually achieved by reacting methyl 5-chloropentanoate with sodium azide. First, sodium azide and sodium carbonate were dissolved in aqueous ammonia, then methyl 5-chlorovalerate was added to the reaction solution, and the reaction was stirred at a low temperature for several hours. Finally, the target product is obtained by extraction and purification steps.
Safety Information:
- 5-Azidopentanoic acid methyl ester is explosive when suspended in air because it is an azido compound. Therefore, care must be taken during use and contact with open flames, high temperatures and intense reaction conditions must be avoided.
-It is irritating to the eyes and skin and should be avoided. Wear appropriate protective gloves and eye protection during operation.
-When storing and handling, it should be kept away from combustibles and oxidants, and stored in a nitrogen-filled environment to reduce the risk of explosion.
Please note that for handling and using any chemicals, always follow safe operating procedures and ensure that appropriate training and equipment are available. In all cases, the safety data sheets and instructions provided by the manufacturer shall be followed.
Nature:
-Appearance: Colorless to light yellow oily liquid.
-Molecular formula: C6H9N3O2.
-Molecular weight: 155.16g/mol.
-Melting Point: Unknown.
-Boiling point: 215-220°C(0.15 mmHg).
-Solubility: Soluble in most organic solvents, such as ethanol, chloroform and dimethylformamide.
Use:
- 5-Azidopentanoic acid methyl ester is a commonly used chemical reagent, which is widely used in organic synthesis and biochemical research.
-It can be used as a donor for azido groups, and an alkyne click reaction (click chemistry) occurs during the synthesis process, which is used to build a variety of biologically active molecules.
Preparation Method:
-The synthesis of 5-Azidopentanoic acid methyl ester is usually achieved by reacting methyl 5-chloropentanoate with sodium azide. First, sodium azide and sodium carbonate were dissolved in aqueous ammonia, then methyl 5-chlorovalerate was added to the reaction solution, and the reaction was stirred at a low temperature for several hours. Finally, the target product is obtained by extraction and purification steps.
Safety Information:
- 5-Azidopentanoic acid methyl ester is explosive when suspended in air because it is an azido compound. Therefore, care must be taken during use and contact with open flames, high temperatures and intense reaction conditions must be avoided.
-It is irritating to the eyes and skin and should be avoided. Wear appropriate protective gloves and eye protection during operation.
-When storing and handling, it should be kept away from combustibles and oxidants, and stored in a nitrogen-filled environment to reduce the risk of explosion.
Please note that for handling and using any chemicals, always follow safe operating procedures and ensure that appropriate training and equipment are available. In all cases, the safety data sheets and instructions provided by the manufacturer shall be followed.
Last Update：2024-04-10 22:29:15
